"Does this coffee taste a little queeny? Or is it just me?"

Overcome with excitement, Izzie spills orange juice all over her big check but fortunately doesn't ruin it. George and Meredith implore her to deposit it right away, and Izzie insists she will as soon as she has a chance to run to the hospital and clean all the antipsychotic meds out of her locker.

"OOH, you know what I'll make when I get back home tonight??"

"A ZOLOFT UPSIDE-DOWN CAKE!!!!!"

At the hospital, the interns hang around talking about what they'd do with that much money. They all concur that Izzie is insane. She overhears this and retorts that Meredith is the one with the problems—after all, she still hasn't fessed up to He-Shepherd that she dumped the vet. Meredith rationalizes endlessly and says He-Shepherd just has a lot on his plate right now, what with the ginger-haired adulteress he's trying to divorce.

"Okay, once I put the handcuffs on, our safe word will be albóndigas"

Dr. Torres and Dr. Sloan apparently no longer work for a living, as they're still lounging around in bed post-coitus. Callie's phone rings with a call from George, but she declines to answer, seeing as she's fully unclothed in the presence of another man's penis. Dr. Sloan wheedles her about her "boyfriend" calling, but Callie insists George is no such thing.

In her morning greeting/diatribe, Bailey tells the interns they're required to go to some event called an "M&M," even if they haven't yet finished their rounds. Apparently this "Morbidity and Mortality Conference" is a monthly meeting all the SGH doctors attend in order to discuss any serious medical mistakes they've made—particularly those that contributed to patient deaths. Oh great, sounds like yet another way to work Denny back into the plot. First Denny's father, then a voicemail message, then the check for Izzie, and now this? For god's sake, JUST DIE ALREADY. I thought we took care of this last May.

Right before the M&M starts, a young couple shows up at the hospital—the wife is in a sour mood because she has breast cancer and is scheduled to have a mastectomy the next day. The husband, for whatever reason, is really giddy. Who knows—maybe he just doesn't like breasts. Anyway, the interns speculate that maybe the woman's diagnosis came so late because she was breastfeeding and assumed the lump in her breast was just a clogged milk duct. Eww. I don't like it when we start mixing medicine and dairy.

Anyway, the interns run to the M&M. Cristina is so eager she even brought snacks. This behavior is HIGHLY unamusing to Dr. Burke, who perhaps was already in a bad mood because he failed to find any gays to stomp on during his morning commute. Dr. Torres gives George the cold shoulder on the way into the auditorium, prompting George to whine that she's just trying to make him feel guilty. FYI, the heavy-handed theme for this week is guilt. Good old-fashioned Catholic guilt. OOH, maybe this this week's special guest star will be THE HOLY FATHER POPE BENEDICT XVI.