Cuddy cares more about public safety than Foreman (and it seems cold, but I see her point). So House decides to have Foreman do an old-timey pickaxe autopsy on Joe, as they're still in quarantine together. But alas and alack, Foreman is already blind, and does a really effective autopsy on Joe's...mattress. Foreman of course doesn't yet know that he's blind. Also, Foreman's advancing quicker than Joe did, which means they have even less time to find a cure. In the office, House, Cameron and Chase are going over every possible disease option, and House decides to treat Foreman for all of those options. They give Foreman quite the drug cocktail, with about 15 different pills. He's being a big brat about how they obviously have no idea what's wrong, but dude? They're trying.

House dons a hazmat suit himself and heads into Joe's apartment with his pet rat, Steve McQueen. He has Foreman retrace his steps over the phone and exposes the rat to all potential toxins. This segues into Foreman Being Vulnerable, as he decides to call his dad and tell him he's sick. Back in rat land, House has set up a webcam on Steve's cage, though he tells Wilson it's of Cuddy's shower. He believes the rat is already euphoric because he's climbing on his water bottle. Then, there's a weird scene in the clinic that I really don't want to go into, before we head to Foreman's where his vision is returning. They want to wean him off his medications one at a time, but unfortunately they're already ruining Foreman's liver with the mai tai of drugs they're giving him.

House is in mean mode as he asks Foreman if he wants to die four hours from now or 14 hours from now. Oh, the options! If he goes off the medications he'll go blind again, but he'll live longer because his pancreas won't shut down. Later, Foreman lies to his dad about the pain level, saying that Joe died in his sleep without much suffering. Aw, that's kind of sweer, and definitely sad. Things get even sadder as Foreman and his dad decide not to tell Foreman's brother. Then, we learn that Foreman's mom has Alzheimer's. Foreman's dad isn't going to tell his wife that Foreman's sick, because she'll just get upset and then forget. Damn.

Montage of sadness as Foreman goes blind again, his dad prays in the chapel and Cuddy cries in her office. The doctors reconvene in the office to discuss variables in the case, and Cameron points out that Foreman's black, and therefore more susceptible to certain ailments. Oh yeah, the writers went there! How daring!